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Articles in Journal

Catching Them Early: Framework Parameters and Progress for Prenatal and Childhood Application of Advanced Therapies

Lederer C.W, Koniali L, Buerki-Thurnherr T, Papasavva P.L, La Grutta S, Licari A, Staud F, Bonifazi D, Kleanthous M.

Pharmaceutics 2022, 14, 793.


Medical Device Development for Children and Young People—Reviewing the Challenges and Opportunities

P. Dimitri, V. Pignataro, M. Lupo, D. Bonifazi , M. Henke , U. M. Musazzi, F. Ernst, P. Minghetti, D. F. Redaelli, S. G. Antimisiaris, G. Migliaccio, F. Bonifazi, L. Marciani, A. J. Courtenay, N. Denora, A. Lopedota

Pharmaceutics 2021, 13(12), 2178;


The GluN2B-Selective Antagonist Ro 25-6981 Is Effective

P. Mareš, L. Kozlová , A. Mikulecká, H. Kubová

Pharmaceutics 2021, 13, 1482;


Children’s Preferences for Oral Dosage Forms and Their Involvement in Formulation Research via EPTRI (European Paediatric Translational Research Infrastructure)

E. Alessandrini, F. Brako, M. Scarpa, M. Lupo , D. Bonifazi, V. Pignataro, M. Cavallo, O. Cullufe, C. Enache, B. Nafria, J. Claverol, L. De Taeye, E. Vermeulen, J. Preston, C. Tuleu

Pharmaceutics 2021, 13, 730;

Detection of Breathing Movements of Preterm Neonates by Recording Their Abdominal Movements with a Time-of-Flight Camera

F. C. Wiegandt, D. Biegger , J. F. Fast, G. Matusiak, J. Mazela, T. Ortmaier, T. Doll, A. Dietzel, B. Bohnhorst, G. Pohlmann

Pharmaceutics 2021, 13, 721;


Drug Safety in Translational Paediatric Research: Practical Points to Consider for Paediatric Safety Profiling and Protocol Development: A Scoping Review

B. Aurich, E. Jacqz-Aigrain

Pharmaceutics 2021, 13, 695;


Breath-Triggered Drug Release System for Preterm Neonates

F. C. Wiegandt, U. P. Froriep, F. Müller, T. Doll, A. Dietzel, G. Pohlmann

Pharmaceutics 2021, 13, 657;


Human Microbiome in Children, at the Crossroad of Social Determinants of Health and Personalized Medicine

Talía Sainz, Valeria Pignataro, Donato Bonifazi, Simona Ravera, María José Mellado, Antonio Pérez-Martínez , Adela Escudero, Adriana Ceci and Cristina Calvo

Children 2021, 8, 1191;


The Neonatal and Juvenile Pig in Pediatric Drug Discovery and Development

M. Ayuso, L. Buyssens, M. Stroe, A. Valenzuela, K. Allegaert, A. Smits, P. Annaert, A. Mulder, S. Carpentier, C. Van Ginneken, S. Van Cruchten

Pharmaceutics 2021, 13/3; doi: 10.3390/pharmaceutics13030415


Patient-Derived Induced Pluripotent Stem Cells (iPSCs) and Cerebral Organoids for Drug Screening and Development in Autism Spectrum Disorder: Opportunities and Challenges

C. Villa, R. Combi, D. Conconi, M. Lavitrano

Pharmaceutics 2021, 13/2; doi: 10.3390/pharmaceutics13020280



Ethical, Legal and Regulatory Issues of Paediatric Translational Research. Call for an Adequate Model of Governance

A. Altavilla, V. Giannuzzi, M. Lupo, D. Bonifazi, A. Ceci

European Journal of Health Law 2020, May 18; doi: 10.1163/15718093-bja10010


Pediatric Biobanking: Kids Are Not Just Little Adults

D. R. Catchpoole, D. Carpentieri, S. Vercauteren, L. Wadhwa, W. Schleif, L. Zhou, J. Zhou, R. M. Labib, E. Smits, E. H. Conradie

Biopreservation and Biobanking 18/4, 2020, August; doi: 10.1089/bio.2020.29071.djc








Chapter in book

Challenges and New Frontiers in the Paediatric Drug Discovery and Development

A. Intini, D. Bonifazi, G. Migliaccio

Drug Discovery and Development – New Advances, 2019; 10.5772/intechopen.85635


EPTRI Special Issues

Special Issue dedicated to the Scientific Highlights in the European Paediatric Translational Research Infrastructure has been published into the section “Drug Delivery and Controlled Release” of the Pharmaceutics Journal at the end of 2021.  

The Special Issue has been addressed to all researchers and partners involved in the development of paediatric medicines working on the following topics: i) paediatric medicines drug targets and methods of identification; ii) advanced cellular/in vitro models for paediatric drug targeting; iii) paediatric formulations and toxicology of drugs; iv) drug delivery design in paediatrics; v) translational research. 

The EPTRI members published 12 articles in this Special Issue.