The Paediatric Biomarkers TRP provides different technologies and expertise to promote biomarker’s research in the paediatric setting in order to identify, characterise and validate new biomarkers for diagnosis, prognosis and personalised therapy in paediatric diseases, and evaluate the paediatric variability with respect to adult biomarkers.
The platform also give access to quality controlled biosamples suitable for research on paediatric biomarkers.
Access to/deposit of annotated paediatric biological samples.
RNA transcripts and DNA variants Biomarker identification and characterisation in paediatric samples.
Protein Biomarker identification and characterisation in paediatric samples.
Metabolite candidate Biomarker identification and characterisation in paediatric samples.
Bioinformatics for the analysis of the data generated by omics platform.
Verification in paediatric samples of the presence and levels of biomarkers (metabolites, proteins, RNA transcripts, DNA variants) that had been previously identified in adult samples or other candidate biomarkers.
Scientific advice on specific research questions.